2008 Brain Development

Multi-modal Neuroimaging Training Program (MNTP)
Symposium on “Brain Development”
July 24-25

Mellon Institute
4400 Fifth Avenue
Pittsburgh, PA 15213

Description: A major research area in modern neuroscience is brain development.  Important topics in this field include the mechanisms of neural circuit formation and plasticity in normal circuits, the development of cognitive abilities and the etiology of neurodevelopmental disorders.  Because development is by definition a process of change, it is often better understood by time lapse imaging approaches or minimally invasive techniques or both.  This has inspired innovation both at the level of neuroimaging technologies and at the level of experimental design.  The 2008 Multimodal Neuroimaging Training Program Symposium on Brain Development has been organized to highlight several aspects of this innovation as well as the data these techniques have made possible.  Funded by NIH (R90DA023420).

July 24, 2008

12:00 – 1:00 p.m.              Registration (Social Room, MI 328)

Session 1: Cellular Imaging (Conference Room, MI 348)

1:00 ñ 1:05 p.m. Welcome and opening remarks
1:05 ñ 1:55 p.m. Tom Mrsic-Flogel, University College London, Department of Neuroscience, Physiology and Pharmacology ìInvestigating functional organization and plasticity of visual cortex with two-photon calcium imagingî
2:00 ñ 2:50 p.m. Alison Barth, Carnegie Mellon, Department of Biological Sciences and Center for Neural Basis of Cognition (CNBC) ìVisualizing neural activity at long time scales using a fosGFP transgenic mouseî
3:00 ñ 3:50 p.m. Edward Ruthazer, McGill University, Montreal Neurological Institute, Department of Neurology and Neurosurgery ìSynaptic control of circuit refinement in the developing visual systemî
4:00 ñ 6:00 p.m. Reception, (Social Room, MI 328)

July 25, 2008

8:30 ñ 9:30 a.m.              Registration and Continental Breakfast, (Social Room, MI 328)

Session 2: Human Imaging (Conference Room, MI 348)

9:30 ñ 10:20 a.m. Beatriz Luna, University of Pittsburgh, Departments of Psychiatry and Psychology and CNBC ìPediatric Neuroimaging: What we have learned about the brain bases of cognitive developmentî
10:20 ñ 11:10 a.m. Suzy Scherf, Carnegie Mellon University, Department of Psychology and CNBC ìFaces on the Brain: Developing the Neural Basis of Category-Specific Representationsî
11:10ñ12:00 p.m. Anto Bagic, University of Pittsburgh, Departments of Neurology & Neurosurgery, CABMSI & MEG Program, UPMC Epilepsy Monitoring Unit ìBrain development in the fourth dimension: from fetal MEG to MEG studies of children with epilepsyî
12:00 ñ 1:15 p.m. Lunch, (Social Room, MI 328)

Session 3: Developmental Mechanisms (Conference Room, MI 348)

1:15 ñ 2:05 p.m. Leonard White, Duke University, Departments of Community and Family Medicine and Neurobiology ìImaging the experience-dependent development of direction selectivity in the visual cortexî
2:05 ñ 2:55 p.m. Sonja Hofer, University College London, Department of Neuroscience, Physiology and Pharmacology ìCombining optical methods to reveal structural correlates of experience-dependent plasticity in the visual cortexî
2:55 ñ 3:45 p.m. Justin Crowley, Carnegie Mellon Department of Biological Sciences and CNBC ìProteomic analyses of functionally defined neocortical columnsî
3:45 p.m. Closing remarks, Seong-Gi Kim, University of Pittsburgh, Department of Radiology, Co-Director of MNTP Program, CNBC
4:00 p.m. External speakers meet with MNTP trainees in the Social Room, MI 328, snack provided